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4-MEO-PCP

4-MEO-PCP

4-MEO-PCP

4-MEO-PCP, or 3-Methoxyphencyclidine, is a synthetic dissociative of the arylcyclohexylamine class. 3-MeO-PCP contains cyclohexane, a six member saturated ring, bonded to two additional rings at R1. One of these rings is a piperidine ring, a nitrogenous six member ring, bonded at its nitrogen group. The other ring is an aromatic phenyl ring, substituted at R3 with a methoxy group.

3-MeO-PCP is a PCP derivative and structurally analogous to 4-MeO-PCP.

Although 3-MeO-PCP was once famously described as possessing opioid or dopaminergic activity (based on early phenomenological analysis), this supposition is contradicted by data showing 3-MeO-PCP to be a potent and selective ligand for the NMDA receptor without appreciable affinity for the µ-opioid receptor or dopamine transporter. 3-MeO-PCP was preceded by the less potent dissociative 4-MeO-PCP and first became available as a research chemical in 2011.

This product is sold only for research uses in laboratory settings. Those who work with it are advised to wear the appropriate safety equipment and follow standard safety protocols while handling it.

 

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